Sticking it to Cancer: How Molecular Glues Could Transform Treatment Imagine a therapy that forces rogue cancer-causing proteins to self-destruct. Molecular glues offer just that — a ground-breaking avenue in targeted protein degradation, especially when conventional cancer drugs fail. By Neelabh Datta. These small molecules foster binding interactions between harmful proteins and degradation signallers known as E3 ubiquitin UCL Science Magazine • Beyond
The Fire Within: A Look at the Inflammatory Basis of Schizophrenia Schizophrenia is a complex syndrome where people interpret reality abnormally resulting in hallucinations, delusions, and disordered thinking (‘Schizophrenia’, 2020). The specific mechanism of how this disorder presents is unknown. Could inflammation be the underlying cause of this disorder? By Oriella Stellakis Two case studies informed this theory. The first patient UCL Science Magazine • Biology
Listen To Your Heart: A Patient Perspective on Catheter Ablation Undergoing a heart procedure can be a nerve-wracking experience, especially when it involves a catheter ablation. This is a first-hand account of a patient's personal journey in hospital, shedding light on the daunting procedure of catheter ablation and the promising results it should produce for patients. UCL Science Magazine • Biology
Can We Save Our Collapsing Fisheries? In 2017, 100 million Pacific cod disappeared off southern Alaska’s coast. This 70% reduction (over 2 years), represents an unprecedented crash of fishery worth $100 million annually, and it was caused by an increase in ocean temperatures. By Francesca Young UCL Science Magazine • Chemistry
The Spinning Dorito: The Ideology Behind the Rotary Engine Perhaps all engineering success requires is a bit of unorthodox cognitive exercise. This is definitely the case for the rotary engine, known as the “Spinning Dorito" due to its triangular-shaped rotor. It is an invention that defies conventional wisdom with its unconventional design. By Hovan Cheung UCL Science Magazine • Engineering
Weight Loss Drugs: The Intersection Between Medication, Stigma, and Lifestyle Ozempic, a weight-loss drug, has invaded popular culture. It is not only seen as a rapid, effective method for weight loss but also endorsed by celebrities in the media. Is this medication the quick-fix it is painted to be, or is it damaging health and perpetuating stigma? By Grace Cunningham UCL Science Magazine • Biology
